23937Array ( [TITRE_TRAVAIL] => Array ( [0] => Intraosseous leiomyosarcoma: a rare tumor ) [etablissement] => Array ( [0] => Institut kassab/service adulte ) [nom] => Array ( [0] => Ben mohamed ) [prenom] => Array ( [0] => Oussama ) [email] => Array ( [0] => oussama_benmohamed@hotmail.fr ) [telephone] => Array ( [0] => 55187314 ) [auteurs] => Array ( [0] => Nom prénom / Name Surname: Oussama Ben mohamed Email: oussama_benmohamed@hotmail.fr Hôpital / Hospital: Institut kassab/service adulte Nom prénom / Name Surname: Chedi saadi Email: Chedi.9@hotmail.fr Hôpital / Hospital: Insitut kassab/service adulte Nom prénom / Name Surname: Meddeb mehdi Email: Meddeb.5@hotmail.fr Hôpital / Hospital: Institut kassab/service adulte Nom prénom / Name Surname: Habboubi khalil Email: Haboubi.14@hotmail.fr Hôpital / Hospital: Institut kassab/service adulte Nom prénom / Name Surname: Mondher mestiri Email: Mestiri@hotmail.fr Hôpital / Hospital: Institut kassab/service adulte ) [mots_cles] => Array ( [0] => Leiomyosarcoma; Rare; Tumor; ) [event-id] => Array ( [0] => 3663 ) [statut] => Array ( [0] => 1 ) [forme] => Array ( [0] => none ) [user_email] => Array ( [0] => oussama_benmohamed@hotmail.fr ) [specialite] => Array ( [0] => Chirurgie orthopédique et traumatologique ) [pays] => Array ( [0] => Tunisie ) [texte_abs] => Array ( [0] => Introduction:Leiomyosarcoma of bone is a rare primary osseous sarcoma characterized by smooth muscle differentiation and absence of malignant osteoid formation. Leiomyosarcoma of bone is diagnostically challenging; this can be improved with greater awareness of this entity and the ability to differentiate it from its histologic mimics. Because of its rarity, only a small number of studies are available in the literature. These factors contribute to our limited understanding of its pathology, prognosis, and treatment. Methodology:We report the case of a 40-year-old male with primary bone LMS who presented with a solitary osteolytic lesion with no cortical destruction in the tibia, seen on an x-ray and subsequent computed tomography (CT) scan. The patient accepted to undergo biopsy of the lesion, which revealed the presence of spindle cells with positive reaction for SMA and desmin at immunohistochemical analysis. These results were consistent with a high-grade malignant LMS arising from the bone. Discussion: The patient was operated on with resectiin of 10.5 cm of tibial bone and centromedullary nailing after a welldone prepation. The main differential diagnoses of primary bone leiomyosarcoma include osteosarcoma, chondrosarcoma, myxofibrosarcoma, synovial sarcoma, malignant peripheral nerve sheath tumor (MPNST), fibrosarcoma, undifferentiated pleomorphic sarcoma and metastatic carcinoma. Results: the histological final study confirmed the original diagnosis with healthy resection limits. After more than 1 year of surgery, the patient is well, with no evidence of recurrent or metastatic disease. Follow-up is ongoing. Conclusion: This case illustrates the need for the radiologist to carefully evaluate and appreciate nonspecific lesions with potentially aggressive imaging features. The case also provides experiental evidence with regard to an extremely rare,though clinically important intra-osseous tumor : primary leiomyosarcoma of bone. ) [rank_math_internal_links_processed] => Array ( [0] => 1 ) [ple-content_has_sections] => Array ( [0] => ) [_eael_post_view_count] => Array ( [0] => 15 ) [trx_addons_post_views_count] => Array ( [0] => 13 ) [ekit_post_views_count] => Array ( [0] => 13 ) [trx_addons_post_likes_count] => Array ( [0] => 0 ) )